A Modern, Non-Surgical Approach to Penile Curvature
Peyronie’s disease is a connective tissue disorder characterized by the development of fibrous scar tissue (plaque) within the penis. This plaque can lead to penile curvature, pain, shortening, and erectile dysfunction, significantly impacting quality of life and sexual confidence.
At Prestige Medical Group, we offer an advanced regenerative approach for appropriate candidates that combines precise plaque needling with platelet-rich plasma (PRP) — a treatment concept supported by emerging urology research and commonly associated with PRP-based protocols such as the P-Shot®.
Understanding Peyronie’s Disease
Peyronie’s disease occurs when abnormal scar tissue forms within the tunica albuginea, the elastic sheath surrounding the erectile chambers. During erections, this hardened plaque prevents normal expansion, causing curvature or deformity.
Symptoms may include:
- Penile curvature or bending during erection
- Palpable hardened plaque or nodules
- Penile pain (especially in early or “active” phases)
- Erectile dysfunction
- Loss of length or girth
While some cases stabilize on their own, many men seek treatment when symptoms persist or worsen.
How PRP with Plaque Needling Works
This treatment approach is designed to mechanically disrupt scar tissue while delivering biologic growth factors directly into the affected area to support tissue remodeling.
Step 1: Precision Plaque Needling
Using controlled, physician-guided techniques, the plaque is gently needled or “tunneled”. This process:
- Breaks up dense fibrotic tissue
- Creates micro-channels within the plaque
- Stimulates a localized healing response
Step 2: PRP (Platelet-Rich Plasma) Injection
PRP is derived from the patient’s own blood and contains concentrated growth factors known to support healing and tissue regeneration. Once prepared, PRP is injected into and around the plaque to:
- Promote collagen remodeling
- Support improved blood flow
- Encourage healthier tissue regeneration
This combined approach leverages both mechanical stimulation and biologic signaling, aiming to soften plaque and improve penile flexibility over time.
What the Research Suggests
Clinical studies and pilot trials evaluating intralesional PRP for Peyronie’s disease have demonstrated:
- Favorable safety profiles
- Potential improvements in curvature and sexual function
- Reduced plaque density in some patients
Some investigational protocols specifically include plaque needling prior to PRP injection, recognizing that mechanical disruption may enhance the effectiveness of regenerative therapies.
While PRP for Peyronie’s disease is still considered investigational, results to date are promising, and ongoing research continues to refine protocols and patient selection.
Who May Be a Candidate?
This regenerative approach may be appropriate for men who:
- Have stable or early-stage Peyronie’s disease
- Are seeking a non-surgical alternative
- Wish to avoid penile implants or invasive surgery
- Have persistent curvature, plaque, or ED symptoms
A comprehensive consultation and ultrasound evaluation are essential to determine candidacy.
Benefits of PRP-Based Peyronie’s Treatment
- Minimally invasive
- Uses your body’s own healing factors
- No synthetic fillers or foreign substances
- Little to no downtime
- May be combined with penile modeling or shockwave therapy
Schedule a Consultation
If Peyronie’s disease is affecting your confidence, comfort, or sexual health, you don’t have to navigate it alone. Our experienced medical team at Prestige Medical Group offers discreet, evidence-informed solutions tailored to your goals.
📍 18302 Irvine Blvd #200, Tustin, CA 92780
📞 (949) 825-7650
🌐 prestigemedigroup.com