This is performed for the treatment of bladder cancer. A small tube is inserted into the bladder through the urethra using local anesthesia. BCG, an immunotherapy agent that is a weakened form of the tuberculosis bacterium, is then instilled into the bladder and the catheter is removed. . It takes approximately 60 seconds to perform but expect to be at the appointment for 15 minutes. You will be asked to hold the medicine for one hour; you do not need to remain in the office for this length of time. There is no preparation and you may drive yourself to and from the appointment. After effects may include blood in the urine, increased urgency and frequency to urinate and burning during urination.